Medications to prevent migraine have been slow in coming, but a treatment approach currently being studied suggests that a new type of drug may benefit countless migraineurs. This new method employs agents that block a protein called calcitonin gene-related peptide (CGRP), which plays a crucial role in migraine. The new drugs, anti-CGRP antibodies, bind to the protein and stop it from attaching to nerve receptors, preventing migraine in the process.

Pregnant women should not use certain preventive migraine medications because the drugs have been linked to lower IQ scores in children who were exposed to these drugs in the womb, according to the U.S. Food and Drug Administration (FDA). Pregnant women should avoid taking valproate sodium and related medications. Valproate products include valproate sodium (Depacon), divalproex sodium (Depakote, Depakote CP and Depakote ER), valproic acid (Depakene and Stavzor) and their generics.

Merck & Co., Inc. has been pursuing a new migraine medication, called telcagepant, which blocks the action of a chemical called calcitonin gene-related peptide, or CGRP. CGRP has been implicated in migraine in a number of studies. The drug, which has completed phase III studies, has been heralded as an exciting advance because it's a completely new compound that is not a vasoconstrictor, unlike the triptan drugs, so is less likely to cause cardiovascular issues in those with pre-existing risk factors.

There are currently seven triptan medications available in the United States. Almotriptan — Axert® (Tablet) Recommended dose One 6.25 mg or 12.5 mg dose after the first sign of migraine No more than two doses in 24 hours Most common side effects Tingling of the skin Burning or prickly feeling Numbness Dizziness Dry mouth Headache Nausea Sleepiness Eletriptan — Relpax® (Tablet) Recommended...

Opioid (narcotic) analgesics are pain relievers which are chemically related to morphine and used fora variety of conditions and circumstances, including the treatment of migraine when other medications fail or are ineffective. Opioids work by blocking pain messages sent to the brain, thereby altering the brain’s perception of pain. As a powerful and highly effective pain reliever, opioids continue to be commonly prescribed for a number of pain states.