Diflunisal (the generic name for Dolobid®) is a nonsteroidal anti-inflammatory analgesic.  It is a prostaglandin inhibitor and similar to Alleve® and Motrin®. It works for moderate to severe pain and is not habit forming. As with other medications in this class, it may make stomach ulcers worse or cause upper gastrointestinal bleeding.  It can have effects on kidney and liver functioning when used chronically.