Headache can be a primary symptom of PMS. PMS is one of the more difficult conditions to treat and its headaches equally as difficult to manage.
If one is experiencing headache prior to, during, or immediately after menses, the use of nonsteroidal anti-inflammatory agents (compounds used to treat arthritis) ergotamine tartrate, or one of the triptans may be helpful in controlling these symptoms. In some patients, antidepressants such as fluoxetine are used to ameliorate PMS symptoms.
Migraine predominantly associated with menses is referred to as menstrual migraine.