Another entry in the race to develop a new generation of migraine treatments is showing promise. Lasmiditan (also known as COL-144) was found to be effective for acute migraine attacks in a Phase IIb study. CoLucid Pharmaceuticals, Inc. describes the drug as "a first-in-class Neurally Acting Anti-Migraine Agent (NAAMA) designed to deliver efficacy in migraine without the vasoconstrictor activity associated with previous generations of migraine therapy. COL-144 selectively targets 5HT1F receptors expressed in the trigeminal nerve pathway."

Indomethacin (Indocin®) is an analgesic. It is classified as a nonsteroidal anti-inflammatory drug. These are commonly referred to as NSAIDS. Other NSAIDS are also used as analgesics. Indomethacin can be used as a pain reliever or analgesic. It can also be used as a treatment for arthritis, fever or other conditions where inflammation plays a role in creating the symptoms.

Ibuprofen is an analgesic. It is classified as a nonsteroidal anti-inflammatory drug, commonly referred to as NSAIDS. Other NSAIDS are also used as analgesics. Ibuprofen can be used as a pain reliever or analgesic. It can also be used as a treatment for arthritis, fever...