Tricyclic antidepressants help to preserve catecholamines* in the brain. They include amitriptyline (Elavil®), protriptyline (Vivactil®), nortriptyline (Pamelor®), imipramine (Tofranil®), desipramine (Norpramin® and Pertofrane®), and doxepin (Sinequan®). These medications are often used in patients who experience frequent, daily or near-daily headaches.