Flowers Patients with chronic migraine are often hypersensitive to stimuli, including light, sound, and odors. In fact, some researchers believe the aversion to odors, osmophobia, is particularly helpful in a differentiating migraine from other headache disorders. Now, new research suggests that patients with chronic migraine (CM) do not experience a significant change in their sense of smell between migrainous and non-migrainous periods, but they appear more likely to have an abnormal sense of smell at baseline compared to their peers who do not experience migraine.