There are currently seven triptan medications available in the United States.

Almotriptan — Axert® (Tablet)

Recommended dose

  • One 6.25 mg or 12.5 mg dose after the first sign of migraine
  • No more than two doses in 24 hours

Most common side effects

  • Tingling of the skin
  • Burning or prickly feeling
  • Numbness
  • Dizziness
  • Dry mouth
  • Headache
  • Nausea
  • Sleepiness

Eletriptan — Relpax® (Tablet)

Recommended dose

  • One 20 mg or 40 mg dose at the start of a migraine
  • No more than two 20 mg or 40 mg doses may be taken in a 24-hour period

Most common side effects

  • Dizziness
  • Lack or loss of strength
  • Nausea
  • Sleepiness or unusual drowsiness
  • Pain or pressure sensation in the chest or throat

Frovatriptan — Frova® (Tablet)

Recommended dose

  • One 2.5 mg tablet after the start of a migraine
  • No more than three should be taken in a 24-hour period

Most common side effects

  • Dizziness
  • Fatigue
  • Headache other than migraine
  • Tingling of the skin
  • Dry mouth
  • Flushing (hot flashes)
  • Feeling hot or cold
  • Chest pain
  • Indigestion
  • Pain in the joints or bones

Naratriptan — Amerge® (Tablet)

Recommended dose

  • One 1 mg or 2.5 mg dose at the first sign of a migraine
  • No more than 5 mg in a 24-hour period

Most common side effects

  • Chest pain (severe)
  • Heaviness, tightness or pressure in the chest, throat and/or neck
  • Feeling of burning sensation
  • Sensation of warmth
  • Numbness
  • Sense of tightness around the chest and/or throat
  • Tingling of the skin
  • Dizziness
  • Drowsiness or increased tiredness
  • Nausea and/or vomiting

Rizatriptan — Maxlt®, Maxlt- MLT® (Tablet, Orally Disintegrating Tablets)

Recommended dose

  • One 5 or 10 mg dose at the first sign of a migraine
  • No more than 30 mg in a 24-hour period

Most common side effects

  • Chest pain or heaviness, tightness/pressure in the chest
  • Pounding heartbeat
  • Feeling of burning sensation
  • Sensation of warmth
  • Numbness
  • Sense of tightness around the chest and/or throat
  • Tingling of the skin

Sumatriptan — Imitrex® (Tablet, Nasal Spray Injection)

Recommended dose

  • Dosage varies depending on severity of migraines and type of delivery

Most common side effects

  • Flushing (hot flashes)
  • Tingling of the skin
  • Drowsiness
  • Dizziness
  • Weakness
  • Sensation of warmth or coldness
  • Burning at injection sites (if injection used)
  • Bitter taste at the back of throat (with nasal sprays)

Zolmitriptan — Zomig® (Tablet, Oral Ingesting Tablet, Nasal Spray)

  • Recommended dose
  • Dosage varies depending on severity of migraines and type delivery

Most common side effects

  • Chest pain (severe)
  • Heaviness, tightness, or pressure in chest
  • Feeling of burning sensation
  • Tingling of skin
  • Dizziness
  • Nausea
  • Sensation of warmth
  • Numbness
  • Sense of tightness around the chest and/or throat
  • Sleepiness or unusual tiredness
  • Muscle weakness