Q. I have been a migraine sufferer since my early twenties and am now in my fifties. I have been diagnosed with cluster migraines and, true to pattern, can go two to three years without migraines, except for two to three attacks per month prior to my period. Interesting though, I had no migraines during pregnancy. I am currently taking amitriplyline daily, Imitrex® as needed, and just started taking Topamax® when the headaches began their cycle again. Are these headaches ever going to stop? Does a person outgrow them? After every cluster, I always hope it will be my last time.

Studies have shown that verapamil may be effective in the preventive treatment of migraine and cluster headache patients. Verapamil is a calcium blocker that may work by preventing the constriction of the blood vessels prior to the migraine attack. However, recent genetic studies have suggested that...

The calcium channel blockers are a group of medications that have been used for treating a variety of cardiovascular disorders such as high blood pressure. These medications alter the movement of calcium ions into muscle cells of blood vessels. This effect can sometimes prevent blood vessel changes, which are involved in migraine and cluster headache.