High doses of Vitamin B-2 (riboflavin) may help prevent migraine headaches, a European study reports in the journal Neurology. The beneficial effects in reducing migraine frequency appeared after a month of daily doses of 400 mg, and increased over the next two months, researchers said. The 400 mg daily dose is 200 times the recommended daily allowance of this vitamin. "If you are considering taking this supplement," our pharmacy consultant says, "please speak with your physician and pharmacist about adding this to your daily regimen. Like medications, vitamins also can have side effects."